Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription

<p>Abstract</p> <p>Background</p> <p>HIV-1 Tat protein recruits human positive transcription elongation factor P-TEFb, consisting of CDK9 and cyclin T1, to HIV-1 transactivation response (TAR) RNA. CDK9 is maintained in dephosphorylated state by TFIIH and undergo phosph...

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Bibliographic Details
Main Authors: Brady John, Debebe Zufan, Washington Kareem, Ammosova Tatyana, Nekhai Sergei
Format: Article
Language:English
Published: BMC 2005-07-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/47

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http://www.retrovirology.com/content/2/1/47

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