Solubility Enhancement of Betamethasone, Meloxicam and Piroxicam by Use of Choline-Based Deep Eutectic Solvents

Solubility Enhancement of Betamethasone, Meloxicam and Piroxicam by Use of Choline-Based Deep Eutectic Solvents

Background: The low aqueous solubility of three important drugs (betamethasone (BETA), meloxicam (MEL) and piroxicam (PIR)) have been increased by use of deep eutectic solvents (DESs) based choline chloride/urea (ChCl/U), choline chloride/ethylene glycol (ChCl/EG) and choline chloride/glycerol (ChCl...

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Bibliographic Details
Main Authors: Salva Golgoun, Masumeh Mokhtarpour, Hemayat Shekaari
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2021-03-01
Series:Pharmaceutical Sciences
Subjects:
drug solubility
deep eutectic solvent
betamethasone
meloxicam
piroxicam
activity coefficient model
dissolution thermodynamic
Online Access:https://ps.tbzmed.ac.ir/PDF/ps-27-1-86.pdf

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https://ps.tbzmed.ac.ir/PDF/ps-27-1-86.pdf

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