Telbivudine Reduces Parvovirus B19-Induced Apoptosis in Circulating Angiogenic Cells

Telbivudine Reduces Parvovirus B19-Induced Apoptosis in Circulating Angiogenic Cells

Aims: Human parvovirus B19 (B19V) infection directly induces apoptosis and modulates CXCR4 expression of infected marrow-derived circulating angiogenic cells (CACs). This leads to dysfunctional endogenous vascular repair. Treatment for B19V-associated disease is restricted to symptomatic treatment....

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Bibliographic Details
Main Authors: Thomas Zobel, C.-Thomas Bock, Uwe Kühl, Maria Rohde, Dirk Lassner, Heinz-Peter Schultheiss, Caroline Schmidt-Lucke
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Viruses
Subjects:
telbivudine
B19V
circulating angiogenic cells
apoptosis
caspase-3
BIRC3 (cIAP-2)
Online Access:http://www.mdpi.com/1999-4915/11/3/227

Internet

http://www.mdpi.com/1999-4915/11/3/227

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