Changes in gene expression associated with loss of function of the NSDHL sterol dehydrogenase in mouse embryonic fibroblasts

Changes in gene expression associated with loss of function of the NSDHL sterol dehydrogenase in mouse embryonic fibroblasts

Seven human disorders of postsqualene cholesterol biosynthesis have been described. One of these, congenital hemidysplasia with ichthyosiform nevus and limb defects (CHILD) syndrome, results from mutations in the X-linked gene NADH sterol dehydrogenase-like (NSDHL) encoding a sterol dehydrogenase. A...

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Bibliographic Details
Main Authors: David Cunningham, Daniel Swartzlander, Sandya Liyanarachchi, Ramana V. Davuluri, Gail E. Herman
Format: Article
Language:English
Published: Elsevier 2005-06-01
Series:Journal of Lipid Research
Subjects:
cholesterol biosynthesis
congenital hemidysplasia with ichthyosiform nevus and limb defects syndrome
microarray
bare patches
sterol
development
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520330200

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http://www.sciencedirect.com/science/article/pii/S0022227520330200

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