siRNA against TSG101 reduces proliferation and induces G0/G1 arrest in renal cell carcinoma – involvement of c-myc, cyclin E1, and CDK2

siRNA against TSG101 reduces proliferation and induces G0/G1 arrest in renal cell carcinoma – involvement of c-myc, cyclin E1, and CDK2

Abstract Objective The tumor susceptibility gene 101 (TSG101) is closely associated with various tumor types, but its role in the pathogenesis of renal cell carcinoma (RCC) is still unknown. This study used RNA interference to silence the expression of TSG101 in RCC cell lines and explore the role o...

Full description

Bibliographic Details
Main Authors: Chen Xu, Junhua Zheng
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cellular & Molecular Biology Letters
Subjects:
Renal cell carcinoma
TSG101
Cell proliferation
Cell cycle
Online Access:http://link.springer.com/article/10.1186/s11658-018-0124-y

Internet

http://link.springer.com/article/10.1186/s11658-018-0124-y

Similar Items