Enhanced responses to tumor immunization following total body irradiation are time-dependent.

Enhanced responses to tumor immunization following total body irradiation are time-dependent.

The development of successful cancer vaccines is contingent on the ability to induce effective and persistent anti-tumor immunity against self-antigens that do not typically elicit immune responses. In this study, we examine the effects of a non-myeloablative dose of total body irradiation on the ab...

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Bibliographic Details
Main Authors: Adi Diab, Robert R Jenq, Gabrielle A Rizzuto, Adam D Cohen, Deonka W Huggins, Taha Merghoub, Manuel E Engelhorn, José A Guevara-Patiño, David Suh, Vanessa M Hubbard-Lucey, Adam A Kochman, Suzie Chen, Hong Zhong, Jedd D Wolchok, Marcel R M van den Brink, Alan N Houghton, Miguel-Angel Perales
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3861406?pdf=render

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http://europepmc.org/articles/PMC3861406?pdf=render

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