Atorvastatin Attenuates Programmed Death Ligand-1 (PD-L1) Induction in Human Hepatocellular Carcinoma Cells

Atorvastatin Attenuates Programmed Death Ligand-1 (PD-L1) Induction in Human Hepatocellular Carcinoma Cells

Liver cancer is the sixth most common cancer worldwide with high morbidity and mortality. Programmed death ligand 1 (PD-L1) is a major ligand of programmed death 1 receptor (PD1), and PD1/PD-L1 checkpoint acts as a negative regulator of the immune system. Cancers evade the host’s immune defense via...

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Bibliographic Details
Main Authors: Thuzar Hla Shwe, Peraphan Pothacharoen, Thanyaluck Phitak, Benjawan Wudtiwai, Prachya Kongtawelert
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
PD-L1
IFNγ
TNFα
atorvastatin
liver cancer
HepG2
Online Access:https://www.mdpi.com/1422-0067/22/16/8755

Internet

https://www.mdpi.com/1422-0067/22/16/8755

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