Preliminary investigation of mechanism underlying Klotho insufficiency-induced spontaneous hypertension in mice

Preliminary investigation of mechanism underlying Klotho insufficiency-induced spontaneous hypertension in mice

Objective To investigate the mechanism of Klotho (KL) insufficiency-induced spontaneous hypertension in mice. Methods We monitored blood pressure using high-throughput non-invasive blood pressure cuff in 10-week-old 129Sv mice with partial KL gene knockout (KL+/-) and wide-type 129Sv mice of the sa...

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Bibliographic Details
Main Authors: DONG Zhaoying, ZHOU Xiaoli
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2020-02-01
Series:Di-san junyi daxue xuebao
Subjects:
klotho
high blood pressure
kidney impairment
aldosterone
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/201909150.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/201909150.htm

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