Prognostic Value of the Immunohistochemical Expression of Serine and Arginine-Rich Splicing Factor 1 (SRSF1) in Uveal Melanoma: A Clinico-Pathological and Immunohistochemical Study on a Series of 85 Cases

Prognostic Value of the Immunohistochemical Expression of Serine and Arginine-Rich Splicing Factor 1 (SRSF1) in Uveal Melanoma: A Clinico-Pathological and Immunohistochemical Study on a Series of 85 Cases

Uveal melanoma (UM) is the most frequent primary ocular malignancy of adults; it exhibits an almost invariably poor prognosis with onset of liver metastases within 10–15 years after the diagnosis. Serine and arginine-rich splicing factor 1 (SRSF1) is an RNA-binding protein with proto-oncogene functi...

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Bibliographic Details
Main Authors: Giuseppe Broggi, Luca Falzone, Matteo Fallico, Andrea Russo, Michele Reibaldi, Antonio Longo, Teresio Avitabile, Rocco De Pasquale, Lidia Puzzo, Pietro Valerio Foti, Daniela Russo, Rosa Maria Di Crescenzo, Massimo Libra, Stefania Staibano, Rosario Caltabiano
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Applied Sciences
Subjects:
uveal melanoma
SRSF1
prognostic factor
MVD
metastasis
melanoma
Online Access:https://www.mdpi.com/2076-3417/11/17/7874

Internet

https://www.mdpi.com/2076-3417/11/17/7874

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