Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer’s Disease

Strong evidence has emerged recently for the concept that herpes simplex virus type 1 (HSV1) is a major risk for Alzheimer’s disease (AD). This concept proposes that latent HSV1 in brain of carriers of the type 4 allele of the apolipoprotein E gene (APOE-ε4) is reactivated intermittently by events s...

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Bibliographic Details
Main Author: Ruth F. Itzhaki
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00324/full