Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function

Transgenic modeling of Ndr2 gene amplification reveals disturbance of hippocampus circuitry and function

Summary: Duplications and deletions of short chromosomal fragments are increasingly recognized as the cause for rare neurodevelopmental conditions and disorders. The NDR2 gene encodes a protein kinase important for neuronal development and is part of a microduplication region on chromosome 12 that i...

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Bibliographic Details
Main Authors: Deniz A. Madencioglu, Gürsel Çalışkan, Pingan Yuanxiang, Kati Rehberg, Yunus E. Demiray, Emre Kul, Alexander Engler, Hussam Hayani, Jorge R. Bergado-Acosta, Anne Kummer, Iris Müller, Inseon Song, Alexander Dityatev, Thilo Kähne, Michael R. Kreutz, Oliver Stork
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:iScience
Subjects:
genetics
neuroscience
sensory neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221008361

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http://www.sciencedirect.com/science/article/pii/S2589004221008361

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