Influence of global gene regulatory networks on single cell heterogeneity of green fluorescent protein production in Bacillus subtilis

Influence of global gene regulatory networks on single cell heterogeneity of green fluorescent protein production in Bacillus subtilis

Abstract Background Gram-positive bacterium Bacillus subtilis has been extensively studied as a microbial cell factory for high-level producing a wide range of interesting products. Green fluorescent protein (GFP) is commonly used as a marker for determining the strength of a given promoter or for t...

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Bibliographic Details
Main Authors: Haojie Cao, Oscar P. Kuipers
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Microbial Cell Factories
Subjects:
Bacillus subtilis
Superfolder green fluorescent protein (sfGFP)
Heterogeneous expression
Global transcriptional regulation
Production level
Single cell analysis
Online Access:http://link.springer.com/article/10.1186/s12934-018-0985-9

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http://link.springer.com/article/10.1186/s12934-018-0985-9

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