Yizhiqingxin Formula Alleviates Cognitive Deficits and Enhances Autophagy via mTOR Signaling Pathway Modulation in Early Onset Alzheimer’s Disease Mice

Yizhiqingxin Formula Alleviates Cognitive Deficits and Enhances Autophagy via mTOR Signaling Pathway Modulation in Early Onset Alzheimer’s Disease Mice

Alzheimer’s disease (AD) is the most common type of dementia worldwide. The deposition of amyloid β (Aβ) is one of the most important pathological changes in AD. Autophagy, which mediates degradation of toxic proteins and maintains normal neuronal function, is dysfunctional in AD; dysfunctional auto...

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Bibliographic Details
Main Authors: Yang Yang, Zhiyong Wang, Yu Cao, Jiangang Liu, Peng Li, Hao Li, Meixia Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
Alzheimer’s disease
Yizhiqingxin formula
autophagy
mTOR
APP/PS1 mice
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01041/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01041/full

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