Oral Tolerance Induced by Heat Shock Protein 65-Producing Lactococcus lactis Mitigates Inflammation in Leishmania braziliensis Infection

Oral Tolerance Induced by Heat Shock Protein 65-Producing Lactococcus lactis Mitigates Inflammation in Leishmania braziliensis Infection

Cutaneous leishmaniasis caused by L. braziliensis induces a pronounced Th1 inflammatory response characterized by IFN-γ production. Even in the absence of parasites, lesions result from a severe inflammatory response in which inflammatory cytokines play an important role. Different approaches have b...

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Bibliographic Details
Main Authors: Priscila Valera Guerra, Camila Mattos Andrade, Ivanéia Valeriano Nunes, Brena Cardoso Gama, Rafael Tibúrcio, Washington Luis Conrado Santos, Vasco Ariston Azevedo, Natalia Machado Tavares, Juliana de Souza Rebouças, Tatiani Uceli Maiolii, Ana Maria Caetano Faria, Cláudia Ida Brodskyn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
Leishmania braziliensis
heat shock protein 65
Lactococcus lactis
oral tolerance
IL-10
TLR2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.647987/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.647987/full

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