A promising DNA methylation signature for the triage of high-risk human papillomavirus DNA-positive women.

High-risk human papillomavirus (hrHPV)-DNA testing is frequently performed parallel to cytology for the detection of high-grade dysplasia and cervical cancer particularly in women above 30 years of age. Although highly sensitive, hrHPV testing cannot distinguish between HPV-positive women with or wi...

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Bibliographic Details
Main Authors: Alfred Hansel, Daniel Steinbach, Christiane Greinke, Martina Schmitz, Juliane Eiselt, Cornelia Scheungraber, Mieczyslaw Gajda, Heike Hoyer, Ingo B Runnebaum, Matthias Dürst
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3960142?pdf=render