Sleep restriction prior to antigen exposure does not alter the T cell receptor repertoire but impairs germinal center formation during a T cell-dependent B cell response in murine spleen

It is well known that sleep promotes immune functions. In line with this, a variety of studies in animal models and humans have shown that sleep restriction following an antigen challenge dampens the immune response on several levels which leads to e.g. worsening of disease outcome and reduction of...

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Bibliographic Details
Main Authors: Cornelia Tune, Julia Hahn, Stella E. Autenrieth, Martin Meinhardt, Rene Pagel, Andrea Schampel, Lisa-Kristin Schierloh, Kathrin Kalies, Juergen Westermann
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354621001150