Hybridization of Curcumin Analogues with Cinnamic Acid Derivatives as Multi-Target Agents Against Alzheimer’s Disease Targets

Hybridization of Curcumin Analogues with Cinnamic Acid Derivatives as Multi-Target Agents Against Alzheimer’s Disease Targets

The synthesis of the new hybrids followed a hybridization with the aid of hydroxy-benzotriazole (HOBT) and 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDCI.HCL) in dry DMF or thionyl chloride between curcumin analogues and cinnamic acid derivatives. IR, <sup>1</sup>H-NMR, <sup>1...

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Bibliographic Details
Main Authors: Eirini Chainoglou, Argyris Siskos, Eleni Pontiki, Dimitra Hadjipavlou-Litina
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
curcumin analogues
cinnamic acids
Hybrids
Alzheimer’s disease
therapy
Online Access:https://www.mdpi.com/1420-3049/25/21/4958

Internet

https://www.mdpi.com/1420-3049/25/21/4958

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