Nicotinamide nucleotide transhydrogenase-mediated redox homeostasis promotes tumor growth and metastasis in gastric cancer

Overcoming oxidative stress is a critical step for tumor growth and metastasis, however the underlying mechanisms in gastric cancer remain unclear. In this study, we found that overexpression of nicotinamide nucleotide transhydrogenase (NNT) was associated with shorter overall and disease free survi...

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Bibliographic Details
Main Authors: Shuai Li, Zhuonan Zhuang, Teng Wu, Jie-Chun Lin, Ze-Xian Liu, Li-Fen Zhou, Ting Dai, Lei Lu, Huai-Qiang Ju
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718305457