N-terminal domain of apolipoprotein B has structural homology to lipovitellin and microsomal triglyceride transfer protein: a “lipid pocket” model for self-assembly of apoB-containing lipoprotein particles

N-terminal domain of apolipoprotein B has structural homology to lipovitellin and microsomal triglyceride transfer protein: a “lipid pocket” model for self-assembly of apoB-containing lipoprotein particles

The process of assembly of apolipoprotein (apo) B-containing lipoprotein particles occurs co-translationally after disulfide-dependent folding of the N-terminal domain of apoB but the mechanism is not understood. During a recent database search for protein sequences that contained similar amphipathi...

Full description

Bibliographic Details
Main Authors: Jere P. Segrest, Martin K. Jones, Nassrin Dashti
Format: Article
Language:English
Published: Elsevier 1999-08-01
Series:Journal of Lipid Research
Subjects:
plasma apolipoproteins
LOCATE
microsomal triglyceride transfer protein (MTP)
amphipathic β sheets
amphipathic α helixes
co-translational
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520333824

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520333824

Similar Items