BRAF in Melanoma: Pathogenesis, Diagnosis, Inhibition, and Resistance

Since the initial discovery that a subset of patients with cutaneous melanoma harbor BRAF mutations, substantial research has been focused on determining the pathologic consequences of BRAF mutations, optimizing diagnostic techniques to identify these mutations, and developing therapeutic interventi...

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Bibliographic Details
Main Authors: Ryan J. Sullivan, Keith T. Flaherty
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Skin Cancer
Online Access:http://dx.doi.org/10.1155/2011/423239