The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer

The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer

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<p>Abstract</p> <p>Background</p> <p><it>HER2/neu </it>is an oncogene that facilitates neoplastic transformation due to its ability to transduce growth signals in a ligand-independent manner, is over-expressed in 20-30% of human breast cancers correlating wi...

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Bibliographic Details
Main Authors: Penichet Manuel L, Lu Hailing, Mary Disis L, Gately Stephen, Von-Hoff Daniel, Hurley Laurence H, Bradley-Dunlop Deborah J, Hahn Tobias, Besselsen David G, Cole Brook B, Meeuwsen Tanisha, Walker Edwin, Akporiaye Emmanuel T
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/471

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http://www.biomedcentral.com/1471-2407/11/471

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