A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells

A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells

Oxidative stress is a leading causative agent in the defective sperm function associated with male infertility. Such stress commonly manifests via the accumulation of pathological levels of the electrophilic aldehyde, 4-hydroxynonenal (4HNE), generated as a result of lipid peroxidation. This highly...

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Bibliographic Details
Main Authors: Brett Nixon, Ilana R. Bernstein, Shenae L. Cafe, Maryse Delehedde, Nicolas Sergeant, Amanda L. Anderson, Natalie A. Trigg, Andrew L. Eamens, Tessa Lord, Matthew D. Dun, Geoffry N. De Iuliis, Elizabeth G. Bromfield
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
4-hydroxynonenal
A-kinase anchor protein 4
male germ cells
oxidative stress
spermatozoa
sperm capacitation
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00319/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2019.00319/full

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