MG-132 attenuates cardiac deterioration of viral myocarditis via AMPK pathway

MG-132 attenuates cardiac deterioration of viral myocarditis via AMPK pathway

Background: Coxsackievirus B3 (CVB3) is the primary cause of infectious myocarditis. Aggressive immunological activation and apoptosis of myocytes contributes to progressive dysfunction of cardiac contraction and poor prognosis. MG-132, a proteasome inhibitor, regulates mitochondrial-mediated intrin...

Full description

Bibliographic Details
Main Authors: Xin-Min Zhang, Yue-Chun Li, Peng Chen, Sheng Ye, Shang-He Xie, Wu-Jie Xia, Jun-Hua Yang
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
CVB3
Myocarditis
MG-132
AMPK pathway
Inflammation
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220302833

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220302833

Similar Items