Current Advances of Tubulin Inhibitors in Nanoparticle Drug Delivery and Vascular Disruption/Angiogenesis

Current Advances of Tubulin Inhibitors in Nanoparticle Drug Delivery and Vascular Disruption/Angiogenesis

Extensive research over the last decade has resulted in a number of highly potent tubulin polymerization inhibitors acting either as microtubule stabilizing agents (MSAs) or microtubule destabilizing agents (MDAs). These inhibitors have potent cytotoxicity against a broad spectrum of human tumor cel...

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Bibliographic Details
Main Authors: Souvik Banerjee, Dong-Jin Hwang, Wei Li, Duane D. Miller
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Molecules
Subjects:
tubulin dynamics
tubulin inhibitors
multidrug resistance
nanoparticle formulations
β-tubulin isotypes and drug resistance
angiogenesis
vascular disrupting agent
antimitotic
Online Access:http://www.mdpi.com/1420-3049/21/11/1468

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http://www.mdpi.com/1420-3049/21/11/1468

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