Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children

Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children

During the first 5 years of life, children are especially vulnerable to infection-related morbidity and mortality. Conversely, the Hygiene Hypothesis suggests that a lack of exposure to infectious agents early in life could explain the increasing incidence of allergies and autoimmunity in high-incom...

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Bibliographic Details
Main Authors: Lisa E. Wagar, Christopher R. Bolen, Natalia Sigal, Cesar J. Lopez Angel, Leying Guan, Beth D. Kirkpatrick, Rashidul Haque, Robert J. Tibshirani, Julie Parsonnet, William A. Petri, Mark M. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
pediatric immunity
CyTOF
environment
immune development
immune profiling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02239/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02239/full

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