Bioengineering of Improved Biomaterials Coatings for Extracorporeal Circulation Requires Extended Observation of Blood-Biomaterial Interaction under Flow

Extended use of cardiopulmonary bypass (CPB) systems is often hampered by thrombus formation and infection. Part of these problems relates to imperfect hemocompatibility of the CPB circuitry. The engineering of biomaterial surfaces with genuine long-term hemocompatibility is essentially virgin t...

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Bibliographic Details
Main Authors: Kris N. J. Stevens, Yvette B. J. Aldenhoff, Frederik H. van der Veen, Jos G. Maessen, Leo H. Koole
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2007/29464