Pre-bilaterian origin of the blastoporal axial organizer

In vertebrate embryos, Wnt/β-catenin signaling induces an organizer area guiding the formation of body axes and inducing extra axes upon transplantation. Here, Kraus et al. show that Wnt ligands also induce an organizer in a sea anemone, indicating that the organizer dates back over 600 million year...

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Bibliographic Details
Main Authors: Yulia Kraus, Andy Aman, Ulrich Technau, Grigory Genikhovich
Format: Article
Language:English
Published: Nature Publishing Group 2016-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11694