Deciphering the Complexity of 3D Chromatin Organization Driving Lymphopoiesis and Lymphoid Malignancies

Deciphering the Complexity of 3D Chromatin Organization Driving Lymphopoiesis and Lymphoid Malignancies

Proper lymphopoiesis and immune responses depend on the spatiotemporal control of multiple processes, including gene expression, DNA recombination and cell fate decisions. High-order 3D chromatin organization is increasingly appreciated as an important regulator of these processes and dysregulation...

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Bibliographic Details
Main Authors: Laurianne Scourzic, Eralda Salataj, Effie Apostolou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
3D chromatin organization
lymphopoiesis
activation
lymphoid malignancies
B cells
T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.669881/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.669881/full

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