Structural basis of αE-catenin–F-actin catch bond behavior
Cell-cell and cell-matrix junctions transmit mechanical forces during tissue morphogenesis and homeostasis. α-Catenin links cell-cell adhesion complexes to the actin cytoskeleton, and mechanical load strengthens its binding to F-actin in a direction-sensitive manner. Specifically, optical trap exper...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-09-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/60878 |