Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

Mitochondria support synaptic transmission through production of ATP, sequestration of calcium, synthesis of glutamate, and other vital functions. Surprisingly, less than 50% of hippocampal CA1 presynaptic boutons contain mitochondria, raising the question of whether synapses without mitochondria ca...

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Bibliographic Details
Main Authors: Heather L Smith, Jennifer N Bourne, Guan Cao, Michael A Chirillo, Linnaea E Ostroff, Deborah J Watson, Kristen M Harris
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
3D serial electron microscopy
synapses
dendritic spines
hippocampus
plasticity
learning and memory
Online Access:https://elifesciences.org/articles/15275

Internet

https://elifesciences.org/articles/15275

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