Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin

A new series of betulin derivatives containing one or two pharmacophores bearing an acetylenic and carbonyl function at the C-3 and/or C-28 positions has been synthesized and characterized by 1H- and 13C-NMR, IR, MS and elemental analyses. The crystal structure of 28-O-propynoylbetulin was determine...

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Bibliographic Details
Main Authors: Maria Nowak, Maria Jastrzębska, Joachim Kusz, Katarzyna Kempińska, Joanna Wietrzyk, Stanisław Boryczka, Ewa Bębenek
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/4/4526