Various Expression Patterns of α1 and α2 Genes in IgA Deficiency

Various Expression Patterns of α1 and α2 Genes in IgA Deficiency

Background: IgA deficiency (IgAD) is the most common immunodeficiency, however the pathogenesis in most cases of IgAD is unknown. There are 2 subclasses of IgA, IgA1 and IgA2, and its heavy chains are encoded by 2 different genes, the α1 and α2 genes. To investigate the molecular pathogenesis of IgA...

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Bibliographic Details
Main Authors: Hiroko Suzuki, Hideo Kaneko, Toshiyuki Fukao, Rong Jin, Norio Kawamoto, Tsutomu Asano, Eiko Matsui, Kimiko Kasahara, Naomi Kondo
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Allergology International
Subjects:
gene expression
IgA subclasses
partial IgA deficiency
selective IgA deficiency
α1 gene deletion
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015306699

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http://www.sciencedirect.com/science/article/pii/S1323893015306699

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