Metabolic Engineering of The Native Monoterpene Pathway in Spearmint for Production of Heterologous Monoterpenes Reveals Complex Metabolism and Pathway Interactions

Metabolic Engineering of The Native Monoterpene Pathway in Spearmint for Production of Heterologous Monoterpenes Reveals Complex Metabolism and Pathway Interactions

Spearmint produces and stores large amounts of monoterpenes, mainly limonene and carvone, in glandular trichomes and is the major natural source of these compounds. Towards producing heterologous monoterpenes in spearmint, we first reduced the flux into the native limonene pathway by knocking down t...

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Bibliographic Details
Main Authors: Chunhong Li, Sreelatha Sarangapani, Qian Wang, Kumar Nadimuthu, Rajani Sarojam
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
limonene synthase
terpenes
secondary metabolites
metabolic engineering
pathway flux analyses
derivatives
Online Access:https://www.mdpi.com/1422-0067/21/17/6164

Internet

https://www.mdpi.com/1422-0067/21/17/6164

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