Modulating glioma-mediated myeloid-derived suppressor cell development with sulforaphane.

Glioblastoma is the most common primary tumor of the brain and has few long-term survivors. The local and systemic immunosuppressive environment created by glioblastoma allows it to evade immunosurveillance. Myeloid-derived suppressor cells (MDSCs) are a critical component of this immunosuppression....

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Bibliographic Details
Main Authors: Ravi Kumar, Tristan de Mooij, Timothy E Peterson, Tatiana Kaptzan, Aaron J Johnson, David J Daniels, Ian F Parney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5493295?pdf=render