Controlled partial transfer hydrogenation of quinolines by cobalt-amido cooperative catalysis
Controlling the partial reduction of quinolines is challenging, given the competing overreduction to tetrahydroquinolines. Here, the authors report a cobalt-amido cooperative catalyst for the selective, partial transfer hydrogenation of quinolines to 1,2-dihydroquinolines with H3N·BH3 as reductant.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-03-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-15118-x |