Prion protein-specific antibodies that detect multiple TSE agents with high sensitivity.

Prion protein-specific antibodies that detect multiple TSE agents with high sensitivity.

This paper describes the generation, characterisation and potential applications of a panel of novel anti-prion protein monoclonal antibodies (mAbs). The mAbs were generated by immunising PRNP null mice, using a variety of regimes, with a truncated form of recombinant ovine prion protein spanning re...

Full description

Bibliographic Details
Main Authors: Sandra McCutcheon, Jan P M Langeveld, Boon Chin Tan, Andrew C Gill, Christopher de Wolf, Stuart Martin, Lorenzo Gonzalez, James Alibhai, A Richard Alejo Blanco, Lauren Campbell, Nora Hunter, E Fiona Houston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3946747?pdf=render

Internet

http://europepmc.org/articles/PMC3946747?pdf=render

Similar Items