Crucial role of androgen receptor in resistance and endurance trainings-induced muscle hypertrophy through IGF-1/IGF-1R- PI3K/Akt- mTOR pathway

Crucial role of androgen receptor in resistance and endurance trainings-induced muscle hypertrophy through IGF-1/IGF-1R- PI3K/Akt- mTOR pathway

Abstract Background Androgen receptor (AR) has been reported to play vital roles in exercise-induced increase of muscle mass in rats, but needs to be further verified and the mechanism behind remains unclear. As AR target genes, insulin growth factor-1 (IGF-1) and IGF-1 receptor (IGF-1R) promote mus...

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Bibliographic Details
Main Authors: Lijun YIN, Lin LU, Xiaojing LIN, Xiaohui WANG
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Nutrition & Metabolism
Subjects:
Androgen receptor
Muscle hypertrophy
Training
IGF-1
IGF-1R
PI3K/Akt/mTOR
Online Access:http://link.springer.com/article/10.1186/s12986-020-00446-y

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http://link.springer.com/article/10.1186/s12986-020-00446-y

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