Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies

Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies

The promyelocytic leukemia (pml) gene product PML is a tumor suppressor localized mainly in the nucleus of mammalian cells. In the cell nucleus, PML seeds the formation of macromolecular multiprotein complexes, known as PML nuclear bodies (PML NBs). While PML NBs have been implicated in many cellula...

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Bibliographic Details
Main Authors: Christian Hoischen, Shamci Monajembashi, Klaus Weisshart, Peter Hemmerich
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Oncology
Subjects:
live cell imaging
fluorescence fluctuation microscopy
super-resolution
promyelocytic leukemia
tumor suppressor
oncogene
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00125/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00125/full

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