Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury.

Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury.

<h4>Background</h4>Loss of integrity of the epithelial and endothelial barriers is thought to be a prominent feature of ventilator-induced lung injury (VILI). Based on its function in vascular integrity, we hypothesize that the angiopoietin (Ang)-Tie2 system plays a role in the developme...

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Main Authors: Maria A Hegeman, Marije P Hennus, Matijs van Meurs, Pieter M Cobelens, Annemieke Kavelaars, Nicolaas J Jansen, Marcus J Schultz, Adrianus J van Vught, Grietje Molema, Cobi J Heijnen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21179479/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21179479/pdf/?tool=EBI

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