The Importance of Mutational Analysis in Chronic Myeloid Leukaemia for Treatment Choice

The Importance of Mutational Analysis in Chronic Myeloid Leukaemia for Treatment Choice

Since their introduction in 2001, tyrosine kinase inhibitors (TKIs) targeting BCR-ABL have become the standard therapy for chronic myeloid leukaemia (CML). While allogeneic hematopoietic stem cell transplant is a recognised curative treatment for CML, TKIs prevent progression to advanced phase in mo...

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Bibliographic Details
Main Authors: Hugues de Lavallade, Aytug Kizilors
Format: Article
Language:English
Published: European Medical Journal 2016-11-01
Series:European Medical Journal Oncology
Subjects:
chronic myeloid leukaemia (cml)
bcr-abl
ponatinib
t315i
mutational analysis
tyrosine kinase inhibitors (tki)
Online Access:https://www.emjreviews.com/oncology/article/the-importance-of-mutational-analysis-in-chronic-myeloid-leukaemia-for-treatment-choice/

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https://www.emjreviews.com/oncology/article/the-importance-of-mutational-analysis-in-chronic-myeloid-leukaemia-for-treatment-choice/

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