8-oxoG DNA Glycosylase-1 Inhibition Sensitizes Neuro-2a Cells to Oxidative DNA Base Damage Induced by 900 MHz Radiofrequency Electromagnetic Radiation

8-oxoG DNA Glycosylase-1 Inhibition Sensitizes Neuro-2a Cells to Oxidative DNA Base Damage Induced by 900 MHz Radiofrequency Electromagnetic Radiation

Background/Aims: The purpose of this study was to explore the in vitro putative genotoxicity during exposure of Neuro-2a cells to radiofrequency electromagnetic fields (RF-EMFs) with or without silencing of 8-oxoG DNA glycosylase-1 (OGG1). Methods: Neuro-2a cells treated with or without OGG1 siRNA w...

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Bibliographic Details
Main Authors: Xiaoya Wang, Chuan Liu, Qinglong Ma, Wei Feng, Lingling Yang, Yonghui Lu, Zhou Zhou, Zhengping Yu, Wei Li, Lei Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
DNA base damage
OGG1
Neuro-2a cells
Radiofrequency electromagnetic fields
Reactive oxygen species
Online Access:http://www.karger.com/Article/FullText/430233

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http://www.karger.com/Article/FullText/430233

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