Copy number variation of mitochondrial genes in Pneumocystis jirovecii according to the fungal load in BAL specimens

Copy number variation of mitochondrial genes in Pneumocystis jirovecii according to the fungal load in BAL specimens

AbstractPneumocystis jirovecii is an unculturable fungus and the causative agent of Pneumocystis pneumonia, a life-threatening opportunistic infection. Although molecular diagnosis is often based on the mtLSU rRNA mitochondrial gene due to its greater sensitivity, physiology and the dynamics of the...

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Bibliographic Details
Main Authors: clara valero, Maria Jose Buitrago, Maud Gits-Muselli, Marion Benazra, Aude Sturny-Leclere, Samia Hamane, Nicolas Guigue, Stephane Bretagne, Alexandre Alanio
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Microbiology
Subjects:
Mitochondria
Pneumocystis jirovecii
Real-Time PCR
PCP
carriage
DNA quantification
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01413/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01413/full

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