Restoration of keratinocytic phenotypes in autonomous trisomy-rescued cells

Restoration of keratinocytic phenotypes in autonomous trisomy-rescued cells

Abstract Background An extra copy of chromosome 21 in humans can alter cellular phenotypes as well as immune and metabolic systems. Down syndrome is associated with many health-related problems and age-related disorders including dermatological abnormalities. However, few studies have focused on the...

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Main Authors: Akiko Tanuma-Takahashi, Momoko Inoue, Kazuhiro Kajiwara, Ryo Takagi, Ayumi Yamaguchi, Osamu Samura, Hidenori Akutsu, Haruhiko Sago, Tohru Kiyono, Aikou Okamoto, Akihiro Umezawa
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Stem Cell Research & Therapy
Subjects:
Keratinocytes
Induced pluripotent stem cells
Trisomy 21
Trisomy rescue
3D skin
Online Access:https://doi.org/10.1186/s13287-021-02448-w

Internet

https://doi.org/10.1186/s13287-021-02448-w

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