Antiproliferative effects of levan polysaccharide against colorectal cancer cells mediated through oxidative stress-stimulated HOTAIR/Akt signaling pathway: In vitro

Antiproliferative effects of levan polysaccharide against colorectal cancer cells mediated through oxidative stress-stimulated HOTAIR/Akt signaling pathway: In vitro

The overexpression of lncRNA HOTAIR can result in cancer progression through upregulation of the Akt signaling pathway. We aimed to evaluate the anticancer effects of levan polysaccharide from Erwinia herbicola on colorectal cancer cells (HT-29) and explore the role of the ROS-mediated HOTAIR/Akt si...

Full description

Bibliographic Details
Main Authors: Tiancheng Zhan, Qian Bai, Zheng Zhao
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Arabian Journal of Chemistry
Subjects:
Levan polysaccharide
Colorectal cancer
Akt
lncRNA
HOTAIR
Signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221004044

Internet

http://www.sciencedirect.com/science/article/pii/S1878535221004044

Similar Items