High APRIL Levels Are Associated With Slow Disease Progression and Low Immune Activation in Chronic HIV-1-Infected Patients

High APRIL Levels Are Associated With Slow Disease Progression and Low Immune Activation in Chronic HIV-1-Infected Patients

Objective: B-cell-activating factor (BAFF) has been determined to be involved in HIV-1 infection and is correlated with disease progression, while its homologous molecule, a proliferation-inducing ligand (APRIL), is less frequently reported, and its role remains unclear. We aimed to characterize the...

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Bibliographic Details
Main Authors: Yubin Liu, Xiuxia Li, Yang Han, Zhifeng Qiu, Xiaojing Song, Bingxiang Li, Han Zhang, Hongye Wang, Kai Feng, Longding Liu, Jingjing Wang, Ming Sun, Taisheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Medicine
Subjects:
APRIL
BAFF
HIV-1 disease progression
antibody response
immune activation
functional cells
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00299/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00299/full

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