NLRP3 inflammasome: the core mechanism and potential target of inflammatory response in Alzheimer's disease

Alzheimer's disease (AD) is the most common cause of cognitive impairment in the elderly. However, the pathogenesis of AD remains unclear. Persistent excessive inflammatory response plays a pivotal role in the development of AD. It has been suggested that activation of the nucleotide-binding ol...

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Bibliographic Details
Main Authors: Jian-quan SHI, Jun XU
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2020-01-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/2079