A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors.

A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors.

Dysregulation of microRNA (miRNA) has been implicated in gastrointestinal stromal tumors (GISTs) but the mechanism is not fully understood. In this study, we aimed to explore the involvement of epigenetic alteration of miRNA genes in GISTs.GIST-T1 cells were treated with 5-aza-2'-deoxycytidine...

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Bibliographic Details
Main Authors: Mai Isosaka, Takeshi Niinuma, Masanori Nojima, Masahiro Kai, Eiichiro Yamamoto, Reo Maruyama, Takayuki Nobuoka, Toshirou Nishida, Tatsuo Kanda, Takahiro Taguchi, Tadashi Hasegawa, Takashi Tokino, Koichi Hirata, Hiromu Suzuki, Yasuhisa Shinomura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4516245?pdf=render

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http://europepmc.org/articles/PMC4516245?pdf=render

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