The Effect of Thermal-Treating on Drug Release from Sustained Release Alginate-Eudragit RS Matrices

Purpose: The main objective of the present study was to develop the colonic delivery system for 5-aminosalicylic acid (5-ASA) as an anti-inflammatory drug. Methods: Matrix pellets containing various proportions of alginate, calcium and Eudragit® RS were prepared by extrusion-spheronization technique...

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Bibliographic Details
Main Authors: Ehsan Kaffash, Mohammadreza Abbaspour, Hadi Afrasiabi Garekani, Zohreh Jahanian, Farinaz Saremnejad, Abbas Akhgari
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2021-02-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Online Access:https://apb.tbzmed.ac.ir/PDF/apb-11-318.pdf