Optical mapping of human embryonic stem cell-derived cardiomyocyte graft electrical activity in injured hearts

Optical mapping of human embryonic stem cell-derived cardiomyocyte graft electrical activity in injured hearts

Abstract Background Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show tremendous promise for cardiac regeneration, but the successful development of hESC-CM-based therapies requires improved tools to investigate their electrical behavior in recipient hearts. While optical voltage mapp...

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Bibliographic Details
Main Authors: Dominic Filice, Wahiba Dhahri, Joell L. Solan, Paul D. Lampe, Erin Steele, Nikita Milani, Benjamin Van Biber, Wei-Zhong Zhu, Tamilla Sadikov Valdman, Rocco Romagnolo, José David Otero-Cruz, Kip D. Hauch, Matthew W. Kay, Narine Sarvazyan, Michael A. Laflamme
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Stem Cell Research & Therapy
Subjects:
Human embryonic stem cells
Cardiomyocyte
Cell transplantation
Optical mapping
Cardiac electrophysiology
Online Access:http://link.springer.com/article/10.1186/s13287-020-01919-w

Internet

http://link.springer.com/article/10.1186/s13287-020-01919-w

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