Effect of VEGF on Inflammatory Regulation, Neural Survival, and Functional Improvement in Rats following a Complete Spinal Cord Transection

Effect of VEGF on Inflammatory Regulation, Neural Survival, and Functional Improvement in Rats following a Complete Spinal Cord Transection

After complete transection of the thoracic spinal segment, neonatal rats exhibit spontaneous locomotor recovery of hindlimbs, but this recovery is not found in adult rats after similar injury. The potential mechanism related to the difference in recovery of neonatal and adult rats remains unknown. I...

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Bibliographic Details
Main Authors: Jing Li, Shuangxi Chen, Zhikai Zhao, Yunhao Luo, Yuhui Hou, Heng Li, Liumin He, Libing Zhou, Wutian Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
spinal cord transection
locomotor function
vascular endothelial growth factor
MAPK signaling
neural circuitry
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00381/full

Internet

http://journal.frontiersin.org/article/10.3389/fncel.2017.00381/full

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